
Vaccines are a safe way to protect oneself from harmful diseases. In the United States, all states require children to be vaccinated for certain diseases before school entry, although the required immunizations vary by state. While vaccination rates in the United States remain high, there are medical, religious, and personal belief exemptions. All 50 states allow children to be exempted from vaccination requirements for medical reasons, which generally include situations where a child's immune status is compromised by a permanent or temporary condition, such as a congenital condition or medications that impair the immune system. However, when children who do not need medical exemptions receive them, vaccination coverage decreases, increasing the number of unvaccinated children susceptible to diseases and the risk of outbreaks.
| Characteristics | Values |
|---|---|
| Immune system | Compromised by a permanent or temporary condition, congenital condition, medication, or illness |
| Allergies | Severe, life-threatening allergies |
| Pregnancy | Pregnant or breastfeeding |
| Previous allergic reaction | Allergic reaction to a previous dose of a vaccine |
| History of illness | History of anthrax, dengue, or cholera |
| Spleen | Non-functioning spleen or no spleen |
| Cerebrospinal fluid leak | Leak of fluid surrounding the brain |
| Guillain-Barré Syndrome | Within 6 weeks after an influenza vaccine |
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What You'll Learn

Allergies
To obtain a medical exemption for allergies, a licensed doctor (MD/DO) must typically sign a form or provide a note explaining the specific medical reasons why the patient cannot receive a particular vaccine. Some states in the US require this exemption form to be renewed annually, and nearly half of the states ask whether the exemption is temporary or permanent.
It is important to note that medical exemptions for allergies should be based on scientific evidence and written consistently with established medical knowledge. However, there have been instances where medical exemptions have been granted based on suspicious or questionable conditions, such as a family history of allergies. This can put children and others at risk of vaccine-preventable diseases, as seen in the recent increase in measles, mumps, and pertussis (whooping cough) outbreaks.
While medical exemptions are necessary for those with legitimate allergies or other medical conditions, it is crucial to maintain high vaccination rates in communities to protect those who cannot get vaccinated due to their medical condition or age. This concept, known as ""herd immunity," helps create a protective barrier around those who are vulnerable to infections but cannot receive vaccines themselves.
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Impaired immune system
In the United States, all states require children to be vaccinated for certain diseases before they can attend school or daycare. However, all 50 states also allow medical exemptions for children who cannot be vaccinated due to health reasons.
An impaired immune system is one of the reasons a child may be exempted from vaccinations. This may be due to a permanent or temporary condition, such as a congenital condition, that impairs the immune system. For example, a child with cancer undergoing chemotherapy or taking steroids may have a weakened immune system, making vaccination unsafe for them.
Additionally, a child with a family history of hereditary or congenital immune system problems may be considered for a medical exemption. This could include a history of severe allergies or autoimmune disorders in the family. However, it is important to note that the decision to grant a medical exemption is made on a case-by-case basis and depends on the specific circumstances of each child.
The process for obtaining a medical exemption varies from state to state. In some states, parents may need to provide a written statement from a physician detailing the medical contraindications to vaccination. Other states may only require a simple form to be filled out. It is important for parents to consult with a healthcare provider to discuss the benefits and risks of vaccination before seeking a medical exemption.
While medical exemptions allow children with impaired immune systems to attend school, they also create a risk for these vulnerable children. Dr. Walter A. Orenstein explains that when unvaccinated children transmit vaccine-preventable diseases, it puts immune-compromised children at risk of infection. This is why "herd immunity" is important—when a large portion of the community is vaccinated, it provides protection for those who cannot be vaccinated due to medical reasons.
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Pregnancy
While there are medical exemptions for certain vaccines, pregnancy is not necessarily one of them. In fact, the CDC recommends that everyone except babies below 6 months of age should get their COVID-19 vaccination and boosters, including people who are pregnant, breastfeeding, or trying to conceive a child.
Pregnant women who contracted COVID-19 were more likely to become severely ill and to be hospitalized than non-pregnant women of the same age and demographics, especially early in the COVID pandemic. A meta-analysis of 435 studies found that pregnant and recently pregnant women who were infected with the virus that causes COVID were more likely to end up in intensive care units, be on invasive ventilation, and die than women who weren’t pregnant but had a similar health profile. This was before COVID vaccines were available.
COVID-19 can pose severe health risks for pregnant women and their unborn babies. During pregnancy, COVID-19 can increase the risk of miscarriage, stillbirth, blood clots, or preterm labour. Studies have demonstrated that pregnant women face a heightened risk of experiencing severe COVID-19 symptoms if infected, compared to non-pregnant women of similar age.
However, there has been much debate and discussion surrounding the topic of COVID-19 vaccines and pregnancy. Health Secretary Robert F. Kennedy Jr. stated that the vaccine would no longer appear on the childhood immunization schedule and that healthy pregnant women do not need COVID boosters. Kennedy, a longtime anti-vaccine activist, announced that COVID vaccines would be removed from the CDC's immunization schedule for healthy pregnant women and healthy children.
Despite this, the CDC's update counters Kennedy's policy, and experts still recommend that pregnant women get vaccinated. Doctors and medical professionals advise that there is no observed reason to consider oneself unsafe if one is pregnant and vaccinated.
Furthermore, multiple studies have proven that the COVID-19 vaccination does not affect one's chances of becoming pregnant. The vaccination decision during pregnancy ultimately depends on each woman's comfort level and risk factors, and it is recommended that they consult with their healthcare provider to make an informed decision.
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Life-threatening allergies
In the United States, all states require children to be vaccinated for certain diseases before they can attend school or daycare. However, all 50 states also allow children to be exempted from vaccination requirements for medical reasons. These exemptions are intended to allow children who cannot be vaccinated for medical reasons to still attend school.
In addition to life-threatening allergies, other valid medical reasons for exemption include a congenital condition that impairs the immune system or the use of medications that impair the immune system, such as chemotherapy or steroids.
It is worth noting that vaccine exemption laws have been linked to outbreaks of diseases like measles, mumps, and pertussis (whooping cough). High exemption rates can lead to an increase in unvaccinated children, who are more susceptible to these diseases. This is why "herd immunity" is important—when a large proportion of the community is vaccinated, it helps protect those who cannot be vaccinated due to medical conditions.
For adults, life-threatening allergies may also be a reason for a medical exemption from mandatory vaccinations in certain cases. The Americans with Disabilities Act (ADA) prohibits discrimination on the basis of disability, and employers must reasonably accommodate disabled employees. However, employers can require verification of the disability and may determine that exempting an employee from vaccination creates an undue burden. In such cases, the employer can require the vaccine as a condition of employment, provided it is job-related and consistent with business necessity.
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History of anthrax disease
The word "anthrax" comes from the Greek word for coal, likely due to the characteristic black skin lesions that develop with a cutaneous anthrax infection. The first recorded use of the word "anthrax" in English was in a 1398 translation of Bartholomaeus Anglicus's work "De proprietatibus rerum" (On the Properties of Things, 1240). However, descriptions of the disease date back to antiquity, with the best ancient account by the Roman poet Virgil.
Anthrax is a potentially fatal and highly contagious infection caused by the bacterium Bacillus anthracis or Bacillus cereus biovar anthracis. It can enter the human body through the intestines (gastrointestinal), lungs (pulmonary), or skin (cutaneous), and causes distinct clinical symptoms based on its site of entry. While anthrax does not typically spread from person to person, if left untreated, pulmonary anthrax is almost always fatal. Cutaneous anthrax, the most common form of transmission, is the least dangerous. Gastrointestinal anthrax, on the other hand, is rare but often fatal if untreated.
Historically, pulmonary anthrax was known as woolsorters' disease as it was an occupational hazard for those working with wool. Today, this form of infection is extremely rare in industrialized nations. The first case of gastrointestinal anthrax in the United States was reported in 1942, and only two cases have been recorded since. In December 2009, a woman in New Hampshire contracted gastrointestinal anthrax, likely from an African drum made with infected animal hide. She became critically ill but eventually recovered.
Anthrax is primarily a disease of livestock, which become infected by ingesting spores found in the soil. Humans usually become infected by handling products of infected animals, such as leather or wool, or by inhaling anthrax spores from these sources. The bacterium that causes anthrax is highly toxic, with a mortality rate of nearly 100% for the inhalation form if untreated. It has been classified as a Category A agent by the Centers for Disease Control and Prevention (CDC), indicating the highest risk for potential use in bioterrorism.
While antibiotics and vaccines exist to prevent and treat anthrax, early and accurate diagnosis is crucial as some strains have already developed antibiotic resistance. The licensed anthrax vaccine in the United States, anthrax vaccine adsorbed (AVA), contains the anthrax protein protective antigen (PA) and has been shown to be effective in preventing the disease.
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Frequently asked questions
Family members with a history of the following diseases may be exempt from vaccines:
- Anthrax
- Dengue
- Cholera
- Typhoid
- Cerebrospinal fluid leak
- Guillain-Barré Syndrome
- Lung disease
- Heart disease
- Kidney disease
- Neurological disorders
Other reasons for medical exemption include:
- A weakened immune system
- Pregnancy or breastfeeding
- Allergies to vaccines or their ingredients
- Previous severe reactions to vaccines
- Taking medication that impairs the immune system
To obtain a medical exemption, you must consult a licensed medical doctor who will evaluate your condition and determine if you meet the criteria for exemption. If you qualify, the doctor will provide a signed form stating the reason for the exemption. This form typically needs to be renewed annually unless a permanent condition is present.

























